鸡眼膏联合液氮冷冻治疗多发性寻常疣的临床疗效分析
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陈悦(1995.8-),女,广东广州人,硕士研究生,医师,主要从事银屑病的发病机制研究

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R752.5+1


Efficacy analysis of Corn Paste combined with Liquid Nitrogen Cryotherapy in the Treatment of Multiple Verruca Vulgaris
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    摘要:

    目的 探讨鸡眼膏(水杨酸苯酚贴膏)联合液氮冷冻治疗多发性寻常疣的临床疗效方法 收集 2020年1月-2021年3月中山大学附属第八医院皮肤科收治的76例多发性寻常疣患者为研究对象,按随机数字表法分为观察组和对照组,每组38例。对照组给予液氮冷冻治疗,观察组给予液氮冷冻联合鸡眼膏治疗,疗程6周。随访6个月,比较两组临床疗效、不良反应、治疗疼痛强度(NRS)、复发情况及皮肤病生活质量指数(DLQI)结果 观察组疣痊愈率和总有效率均高于对照组,痊愈时间短于对照组,NRS评分及并发症发生率均低于对照组,差异有统计学意义(P<0.05);随访6个月,观察组疣复发率、DLQI差值低于对照组,复发时间延迟高于对照组,差异有统计学意义(P<0.05)结论 鸡眼膏联合液氮冷冻治疗多发性寻常疣的临床效果好,治愈率高,并发症少,远期复发率低,患者生活质量改善。

    Abstract:

    Objective To observe the clinical curative effect of corn paste (salicylic acid and plenol plasters) combined with liquid nitrogen cryotherapy in the treatment of multiple verruca vulgaris. Methods From January 2020 to March 2021, 76 patients with multiple verruca vulgaris in the Department of Dermatology, the Eighth Affiliated Hospital, Sun Yat-Sen University were collected as the research objects. According to the random number table, they were randomly divided into an observation group and control group, with 38 cases in each group. Patients in control group were treated with treated liquid nitrogen cryotherapy, who in observation group were treated with corn paste combined with liquid nitrogen cryotherapy, course of treatment for six weeks. The clinical efficacy, adverse reactions, treatment pain intensity (NRS), recurrence and dermatology quality of life indexes(DLQI) of the two groups were compared after follow-up visit for six months. Results The recovery rate and total effective rate of warts in the observation group were higher than those in the control group, the recovery time was shorter than that in the control group, the NRS score and the incidence of complications were lower than those in the control group, and the difference was statistically significant (P<0.05); the wart recurrence rate and DLQI difference in the observation group were lower than those in the control group, and the recurrence time delay was higher than that in the control group, and the differences were statistically significant (P<0.05). Conclusion Corn paste combined with liquid nitrogen cryotherapy have an idea clinical effect in the treatment of multiple verruca vulgaris, which have high cure rate, few complications, low long-term recurrence rate and better quality of life of patients.

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陈悦.鸡眼膏联合液氮冷冻治疗多发性寻常疣的临床疗效分析[J].医学美学美容,2022,31(1):20-23.

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  • 在线发布日期: 2022-08-06