In recent years, with the progress of science and technology and the development of the times, the innovation and reform of medical insurance management in Chinese hospitals have brought great opportunities. In the new era, hospital medical insurance management is gradually developed and toward to informatization. The effective use of information technology in hospital medical insurance management can improve the operation efficiency and management level of hospitals, and help to promote the evolution and development of hospital medical insurance management mode. Therefore, it is necessary to further explore ways to improve the management level of medical insurance system, deeply integrate information technology network with hospital medical insurance system, and reform hospital informatization. The purpose of this paper is to explore the practical role of information management in hospital medical insurance management, in order to provide a scientific basis for the future health management of hospital medical insurance, and lay a foundation for the further exploration and wide application of high-quality health big data in the next stage, so as to further improve the information level of medical insurance management in China.