Double eyelid surgery, as a common cosmetic surgery, has been widely used to improve the eye appearance and shaping beauty. In this field, the continuous progress of medical technology has provided patients with more choices and higher surgical results. As a local anesthetic drug, deszocin in double eyelid surgery has attracted wide attention and research. With the rapid development of medical beauty, many people change their appearance through medical beauty surgery. The application of dezocine can ensure the comfort of the operation process, reduce the pain and discomfort of patients, and also promote postoperative recovery and reduce the occurrence of complications. Therefore, this article will systematically summarize the relevant literature and explore the effect of dezocine on the aesthetics of patients in double eyelid surgery, in order to provide relevant basis for clinical application.