To evaluate the influencing location of impacted teeth, location of lesions and number of impacted teeth between the two groups (P >0.05). Logistic results showed that advanced age, mesial and distal partition (0-1 zone), tooth extraction and orthodontic treatment time >2 years were high risk factors for root resorption of impacted teeth after orthodontic treatment (P <0.05). Conclusion The root resorption of labial inversely impacted maxillary central incisors after orthodontic treatment is related to age, mesial and distal partition, tooth extraction and orthodontic treatment time. For patients with high risk factors, clinical attention should be paid to early intervention measures to reduce injury. factors of impacted teeth occurrence and root resorption in patients with labial inversely impacted maxillary central incisors after orthodontic treatment. Methods The clinical data of 1021 patients with labial inversely impacted maxillary central incisors who were treated in Liyang People's Hospital from March 2019 to March 2021 were collected for retrospective investigation, and cone beam CT and X-ray images were reviewed. Among them, 113 patients were found to have embedded teeth, which were divided into root resorption group (51 patients) and non-root resorption group (62 patients) according to whether there was root resorption. The data were collected, including gender, age of initial diagnosis, average body mass index, location of impacted teeth, mesial and distal partition, tooth extraction, orthodontic treatment time, number of impacted teeth, etc. The above indexes were statistically analyzed, and the single and multiple factors of root resorption of impacted teeth after orthodontic treatment were analyzed. Results Among the 1021 patients, 113 patients (11.07%) had impacted teeth; the average age and the proportion of 2-4 zones in the root resorption group were lower than those in the non-root resorption group (P <0.05). The extraction rate and the proportion of orthodontic treatment time >2 years in the root resorption group were higher than those in the non-root resorption group (P <0.05). There was no significant difference in gender, average body mass index,