To analyze the effect of different soaking time and temperature of traditional chinese medicine fumigation therapy on psoriasis vulgaris. Methods A total of 128 patients with psoriasis vulgaris admitted to our hospital from January 2020 to January 2021 were selected as the research objects. They were divided into A, B, C and D groups according to the ratio of 1:1:1:1 by random number table method, with 32 patients in each group. All subjects were treated with traditional Chinese medicine fumigation and soaking. Group A was intervened at 37 ℃-38 ℃ for 20 min, group B was intervened at 37 ℃-38 ℃ for 30 min, group C was intervened at 39 ℃-40 ℃ for 20 min, and group D was intervened at 39 ℃-40 ℃ for 30 min. The intervention effects and PASI scores of the four groups were compared. Results The total effective rate of intervention in group D was higher than that in groups A, B and C, and the difference was statistically significant (P <0.05). The PASI score of the four groups after intervention was lower than that before intervention, and the differences were statistically significant (P <0.05). There was no significant difference in the main effect of fumigation temperature and the interaction between fumigation temperature and soaking time of traditional Chinese medicine (P >0.05). The main effect of soaking time of traditional Chinese medicine was statistically significant (P <0.05). Conclusion In traditional Chinese medicine fumigation therapy, different soaking time of traditional Chinese medicine will have different effects on the treatment of psoriasis vulgaris, but fumigation temperature has no significant effect on the effect of traditional Chinese medicine fumigation therapy, and different soaking time at different temperatures does not show significant interact ion.