The physiological mechanism of wound formation and wound healing process after medical SPA is complex, involving the interaction between different components, manifested as bleeding, pain, erythema and so on. Related factors such as the intervention of inflammatory factors and the control of the number of bacteria can affect the process of wound repair. As a natural biological material for wound repair, ganoderma lucidum chitosan is a natural polysaccharide with positive charge, with high biocompatibility and low immunogenicity, and does not cause rejection or excessive immune response. Meanwhile, it also has antiinflammatory, antioxidant, antibacterial, and wound healing effects. In recent years, ganoderma lucidum chitosan has shown good repair effect in wounds caused by medical SPA. This paper mainly reviews the classification of medical beauty, wound performance after medical SPA and the application advantages of ganoderma lucidum chitosan in wound repair of medical SPA, in order to provide some reference for the development of ganoderma lucidum chitosan biomaterials in the field of medical beauty.