Objective To explore the application value of photorejuvenation in skin beauty. Methods A total of 72 patients with skin beauty admitted to our hospital from May 2023 to April 2024 were randomly divided into control group and observation group, with 36 patients in each group. The control group was treated with conventional treatment, and the observation group was treated with photorejuvenation. The treatment status, treatment satisfaction and incidence of adverse reactions were compared between the two groups. Results The regression time of pigment and erythema, recovery time of skin lesions and decrustation time in the observation group were shorter than those in the control group (P <0.05). The treatment satisfaction of the observation group was 97.22%, which was higher than 80.56% of the control group (P <0.05). The incidence of adverse reactions in the observation group was 2.78%, which was lower than 16.67% in the control group (P <0.05). Conclusion The application of photorejuvenation technology in skin beauty is ideal. The time of pigment and erythema regression, skin lesion recovery and decrustation is shortened, the patient's satisfaction with cosmetology is high, and the incidence of adverse reactions is low, it is more conducive to recovery and improvement of patients' life happiness index.