Objective To explore the clinical effect of dental implant restoration technology in the treatment of distal-extension absence missing teeth and its influence on masticatory function and aesthetics. Methods From October 2020 to October 2022, 74 patients with distal-extension absence missing teeth admitted to Youde Oral Outpatient Department were selected and divided into active denture group and implant restoration group by random number table method, with 37 patients in each group. The removable denture group received conventional denture restoration treatment, and the implant restoration group received regular implant restoration treatment. The repair effect, tooth masticatory function, tooth aesthetics, tooth stability and repair satisfaction rate were compared between the two groups. Results The total effective rate of restoration in the implant restoration group (97.30%) was higher than that in the removable denture group (83.78%) (P <0.05). The scores of masticatory function and tooth aesthetics in the implant restoration group were higher than those in the removable denture group (P <0.05). There were 35 cases (94.59%) with good tooth stability in the implant restoration group, which was higher than 22 cases (59.46%) in the removable denture group (P <0.05). The repair satisfaction rate of implant restoration group (100.00%) was higher than that of removable denture group (89.19%) (P <0.05). Conclusion Compared with the conventional removable denture restoration method, the use of dental implant restoration technology for the treatment of patients with distal-extension absence missing teeth can effectively improve the repair effect, improve the masticatory function, the stability of the prosthesis, and the patient satisfaction is higher.