Objective To investigate the effect of optimal pulse technology combined with 1565 nm non-ablative fractional laser in the treatment of facial photoaging. Methods A total of 80 patients with facial photoaging admitted to Shanghai Mylike Medical Cosmetology Clinic from January 2023 to March 2024 were selected and divided into control group and observation group according to the random number table method, with 40 patients in each group. The control group was treated with 1565 nm non-ablative fractional laser, and the observation group was treated with optimal pulse technology combined with 1565 nm nonablative fractional laser. The skin melanin index, facial erythema index, stratum corneum hydration, facial wrinkle, skin gloss, skin elasticity and satisfaction were compared between the two groups. Results After 3 months of treatment, the facial melanin index and erythema index in the observation group were lower than those in the control group, and the stratum corneum hydration was higher than that in the control group (P <0.05). After 3 months of treatment, the score of facial wrinkle in the observation group was lower than that in the control group, and the scores of skin gloss and elasticity were higher than those in the control group (P <0.05). The satisfaction rate in the observation group was 100.00%, which was higher than 87.50% in the control group (P <0.05). Conclusion Optimal pulse technology combined with 1565 nm non-ablative fractional laser therapy can improve facial erythema and melanin deposition in patients with facial photoaging, lock in moisture and enhance skin gloss, tightness and elasticity, while patient satisfaction is high.