Objective To explore the effect of oral implant restoration in the treatment of dentition defect and its influence on dental function and aesthetics. Methods From July 2020 to January 2024, a total of 67 patients with dentition defect admitted to the Department of Stomatology, Linyi Lanshan WU Xiaohui Dental Clinic were selected as the research subjects, and they were randomly divided into control group (n =33) and observation group (n =34). The control group was treated with conventional restoration, and the observation group was treated with oral implant restoration. The clinical efficacy, dental function, aesthetics and complication rate of the two groups were compared. Results The total effective rate in the observation group was 94.12%, which was higher than 72.73% in the control group (P <0.05). After treatment, the dental function in the observation group was better than that in the control group (P <0.05). The scores of WES and PES in the observation group were higher than those in the control group (P <0.05). The incidence of complications in the observation group was 5.88%, which was lower than 30.30% in the control group (P <0.05). Conclusion Oral implant restoration is effective in the treatment of dentition defect, which can promote the recovery of patients' oral function, improve the aesthetic effect, reduce the complications, and has high application value.