Objective To analyze the effect of minimally invasive dental implant technology in patients with dentition defect and its influence on oral condition. Methods A total of 80 patients with dentition defect admitted to the Department of Stomatology, Pingyi County Hospital of Traditional Chinese Medicine from March 2022 to December 2023 were selected as the research subjects, and they were randomly divided into control group and observation group, with 40 patients in each group. The control group received routine intervention, and the observation group received minimally invasive dental implant technology intervention. The oral condition, repair effect and aesthetic satisfaction of the two groups were compared. Results The plaque index, gingival bleeding index and gingival index in the observation group were lower than those in the control group (P <0.05). The total effective rate in treatment in the observation group was 100.00%, which was higher than 90.00% in the control group (P <0.05). The satisfaction scores of tooth color, tooth shape, tooth arrangement and smile aesthetics in the observation group were higher than those in the control group (P <0.05). Conclusion The application of minimally invasive dental implant technology in patients with dentition defect is effective, which is beneficial to improve the oral condition of patients, and patient aesthetic satisfaction is high.