Objective To explore the effect of individual nursing based on doctor-nurse integration on patients' incision scar condition after laparoscopic thyroidectomy. Methods A total of 70 thyroid cancer patients who underwent laparoscopic thyroidectomy in our hospital from May 2022 to February 2024 were selected as the research subjects, and they were randomly divided into control group and observation group, with 35 patients in each group. The control group was given conventional nursing, and the observation group was given individual nursing based on doctor-nurse integration on the basis of the control group. The incision scar condition, clinical indexes, negative emotions, quality of life, nursing satisfaction and complications were compared between the two groups. Results The VSS score of the observation group was lower than that of the control group (P <0.05). The incision healing time and hospitalization time in the observation group were lower than those in the control group (P <0.05). After nursing, the scores of SAS and SDS in the observation group were lower than those in the control group (P <0.05). The scores of physiological function, mental health, social function and general health in the observation group were higher than those in the control group (P <0.05). The nursing satisfaction of the observation group was 100.00%, which was higher than 82.86% of the control group (P <0.05). The incidence of complications in the observation group was 2.86%, which was lower than 17.14 % in the control group (P <0.05). Conclusion The application of individual nursing based on doctor-nurse integration after endoscopic thyroid surgery can effectively reduce patients' incision scar, shorten the incision healing time and hospitalization time, as well as help to alleviate patients’ adverse emotions and reduce the risk of complications, which has positive significance for improving patients' postoperative quality of life and nursing satisfaction.