Photoaging, also known as exogenous aging, is caused by long-term and repeated exposure to ultraviolet, resulting in wrinkles, relaxation and discolouration of the skin. The main mechanisms of ultraviolet-induced photoaging include oxidative stress, inflammatory response, glycosylation, apoptosis and so on. Platelet-rich plasma (PRP) is a high-concentration platelet-rich plasma obtained by centrifugation of autologous whole blood. PRP is rich in growth factors and cytokines. Each factor promotes the formation of new cells and blood vessels through interaction, promotes tissue growth and repair, and improves photoaging. This article reviews the research mechanism and treatment progress of PRP in the treatment of photoaging, in order to provide new ideas for clinical treatment of photoaging and provide theoretical basis for more secure and more effective use of PRP in clinical practice.