Objective To investigate the effect of aesthetic restoration of anterior teeth on dental aesthetics and periodontal health indicators in patients with dental fluorosis. Methods From January 2019 to July 2024, 97 dental fluorosis patients admitted to Lanshan WU Xiaohui Dental Clinic were selected as the research subjects, and they were divided into control group (n =48) and observation group (n =49) by the random number table method. The control group was restored with all-ceramic crown, and the observation group was restored with aesthetic restoration of anterior teeth. The dental aesthetics, periodontal health indicators and aesthetic restoration satisfaction were compared between the two groups. Results After treatment, the scores of WES and PES in the observation group were higher than those in the control group (P <0.05). After treatment, the GI, PLI and SBI in the observation group were better than those in the control group (P <0.05). The satisfaction scores of comfort, aesthetics, appearance, colour, personalised feature and gingival margin in the observation group were higher than those in the control group (P <0.05). Conclusion The application effect of aesthetic restoration of anterior teeth in patients with dental fluorosis is accurate, which can effectively improve dental aesthetics and periodontal health indicators, while patients’ satisfaction with the restoration effect is high, which is worthy of clinical application.