Objective To compare the effects of resin infiltration and microabrasion technology on aesthetics restoration effect and teeth sensitivity in patients with dental fluorosis. Methods A total of 90 patients with dental fluorosis admitted to our hospital from January 2022 to January 2024 were selected and randomly divided into control group and study group, with 45 patients in each group. Both groups were restored with cold light whitening technology, while the control group was restored with microabrasion technology, and the study group was restored with resin infiltration. The aesthetics restoration effect, teeth sensitivity and microinvasive degree were compared between the two groups. Results The total effective rate of aesthetics restoration in the study group was 97.78%, which was higher than 82.22% in the control group (P <0.05). After treatment, the score of VAS in the study group was lower than that in the control group (P <0.05). The Carlssion classification result in the study group was better than that in the control group (P <0.05). Conclusion Compared with the microabrasion technology, resin infiltration combined with cold light whitening technology has better microinvasive degree. It can more effectively improve the aesthetics restoration effect of patients with dental fluorosis , and reduce their teeth sensitivity degree.