Peri-implantitis is an infectious disease of peri-implant tissue, but the pathological process, inflammatory response and pathological process of infection are not clear, so it still needs further clinical research. Animal model is an important tool to study the pathogenesis of peri-implantitis. Peri-implantitis models constructed in different animals can be used for basic experimental research. Based on the research progress of domestic and foreign scholars in recent years, this article reviews the different strains of animal models of peri-implantitis, the size selection and implantation site of implants, the induction method of peri-implantitis, the imaging evaluation index and application direction of peri-implantitis, in order to provide reference for relevant scholars.