Objective To explore the efficacy of fractional erbium laser in the treatment of striae gravidarum. Methods A total of 60 parturients with spontaneous vaginal delivery admitted to Wuqiao County People's Hospital from June to December 2022 were selected as the research subjects, and they were divided into the control group and the observation group by the random number table method, with 30 parturients in each group. The control group received conventional treatment, and the observation group received fractional erbium laser treatment. The striae gravidarum condition, clinical effect, pain degree and treatment satisfaction were compared between the two groups. Results After treatment, the striae gravidarum area and the scores of color, roughness and depth in the observation group were better than those in the control group (P <0.05). The total effective rate of treatment in the observation group was 100.00%, which was higher than 80.00% in the control group (P <0.05). The proportion of mild pain and moderate pain in the observation group was higher than that in the control group, and the proportion of intense pain and severe pain was lower than that in the control group (P <0.05). The satisfaction rate in the observation group was 100.00%, which was higher than 63.33% in the control group (P <0.05). Conclusion The effect of fractional erbium laser in the treatment of striae gravidarum is definite. It can improve the condition of striae gravidarum in parturients, relieve their pain, and further improve their treatment satisfaction, which is worthy of clinical application.