海藻酸钠修护敷料对敏感性皮肤红斑患者临床疗效及皮肤状态参数的影响
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方瑞鑫(1985.12-),男,福建漳州人,本科,副主任医师,主要从事皮肤性病科常见病、多发病诊治方面的研究

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R751

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Effect of Sodium Alginate Repair Dressing on Clinical Efficacy and Skin State Parameters in Patients with Sensitive Skin Erythema
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    摘要:

    目的 观察强脉冲光联合海藻酸钠修护敷料治疗敏感性皮肤面部红斑的效果。方法 选取2023年 4月-10月漳州市第二医院收治的85例敏感性皮肤面部红斑患者作为研究对象,采用随机数字表法分为对 照组42例和观察组43例。对照组予以强脉冲光治疗,观察组予以强脉冲光联合海藻酸钠修护敷料治疗, 比较两组临床疗效、皮肤状态参数和皮肤屏障指标及不良反应发生情况。结果 观察组治疗总有效率 (95.35%)高于对照组(90.48%)(P <0.05);观察组治疗后1、2个月红斑面积、血红素指数、凹陷指 数、最大深度均低于对照组(P <0.05);观察组治疗后角质层含水量、表皮油脂含量高于对照组,经皮 水分丢失量低于对照组(P<0.05);观察组不良反应发生率(4.65%)低于对照组(19.05%)(P<0.05)。 结论 强脉冲光联合海藻酸钠修护敷料治疗敏感性皮肤面部红斑效果较好,能有效修复皮肤屏障,同时可 减少不良反应的发生,安全性高,值得临床应用。

    Abstract:

    Objective To observe the effect of intense pulsed light combined with sodium alginate repair dressing in the treatment of facial sensitive skin erythema. Methods A total of 85 patients with facial sensitive skin erythema admitted to the Second Hospital of Zhangzhou from April to October 2023 were selected as the research subjects, and they were divided into the control group (42 patients) and the observation group (43 patients) by the random number table method. The control group was treated with intense pulsed light, and the observation group was treated with intense pulsed light combined with sodium alginate repair dressing. The clinical efficacy, skin state parameters, skin barrier indexes and adverse reactions were compared between the two groups. Results The total effective rate of treatment in the observation group (95.35%) was higher than that in the control group (90.48%) (P <0.05). The erythema area, heme index, depression index and maximum depth in the observation group at 1 and 2 months after treatment were lower than those in the control group (P <0.05). After treatment, the stratum corneum hydration and epidermal oil content in the observation group were higher than those in the control group, and the transepidermal water loss was lower than that in the control group (P <0.05). The incidence of adverse reactions in the observation group (4.65%) was lower than that in the control group (19.05%) (P <0.05). Conclusion The effect of intense pulsed light combined with sodium alginate repair dressing in the treatment of facial sensitive skin erythema is good. It can effectively repair the skin barrier, reduce the incidence of adverse reactions, and has high safety, which is worthy of clinical application.

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方瑞鑫.海藻酸钠修护敷料对敏感性皮肤红斑患者临床疗效及皮肤状态参数的影响[J].医学美学美容,2025,34(5):105-.

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  • 在线发布日期: 2025-03-31
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