Objective To explore the effect of digital technology in occlusion-oriented implant restoration for dentition defect. Methods A total of 80 patients with dentition defect admitted to our hospital from October 2021 to October 2023 were selected as the research subjects. They were divided into the conventional group and the experimental group by the random number table method, with 40 patients in each group. The conventional group received traditional implant restoration treatment, and the experimental group received occlusion-oriented implant restoration treatment based on digital technology. The occlusal function, implant stability, operation time and complications were compared between the two groups. Results The occlusal force and masticatory efficiency of the experimental group were better than those of the conventional group at 3 months after surgery (P <0.05). The ISQ value of the experimental group was higher than that of the conventional group (P <0.05). The operation time of the experimental group was shorter than that of the conventional group (P <0.05). The incidence of complications in the experimental group was 2.50%, which was lower than 17.50% in the conventional group (P <0.05). Conclusion Compared with traditional implant restoration treatment, the application of digital technology in occlusion-oriented implant restoration for dentition defect is more effective, and its operation time is shorter. It can effectively improve the occlusal function and implant stability of patients, and the incidence of complications after restoration is lower. It is a safe and effective treatment method.