Objective To analyze the effect of multi-track specialized nursing under motivational behavior transformation on scar aesthetics in patients with facial tumor. Methods A total of 50 patients with facial tumor admitted to our hospital from June 2021 to June 2024 were selected as the research subjects, and they were divided into the control group and the observation group by the random number table method, with 25 patients in each group. The control group was given routine nursing, and the observation group was given multi-track specialized nursing under motivational behavior transformation on the basis of routine nursing. The scar aesthetics, emotional state, self-care ability, quality of life, nursing compliance and nursing satisfaction were compared between the two groups. Results After nursing, the scores of VSS and PSAS in the observation group were lower than those in the control group (P<0.05). After nursing, the scores of SAS and SDS in the observation group were lower than those in the control group (P<0.05). The scores of each dimension of ESCA in the observation group were higher than those in the control group (P<0.05). The scores of each dimension of GQOLI-74 in the observation group were higher than those in the control group (P<0.05). The nursing compliance rate in the observation group was 96.00%, which was higher than 76.00% in the control group (P <0.05). The nursing satisfaction rate in the observation group was 100.00%, which was higher than 84.00% in the control group (P <0.05). Conclusion For patients with facial tumor, the application of multi-track specialized nursing under motivational behavior transformation to strengthen the intervention is helpful to relieve their negative emotions, enhance their self-care ability, improve nursing compliance, enhance the aesthetics, and promote the improvement of quality of life and nursing satisfaction.