Objective To investigate the effect of progressive nursing based on multi-dimensional coordination on aesthetics in orthodontics patients. Methods A total of 90 orthodontics patients admitted to China-Japan Friendship Hospital from July 2021 to July 2023 were selected as the research subjects, and they were divided into the control group and the observation group by the random number table method, with 45 patients in each group. The control group was given routine nursing, and the observation group was combined with progressive nursing based on multi-dimensional coordination on the basis of the control group. The aesthetic effect, gingival health indexes [periodontal pocket depth (PD), plaque index (PLI) and gingival bleeding index (BI)], dental texture (enamel thickness and roughness), gingival crevicular fluid inflammatory factors [interleukin-6 (IL-6) and interleukin-8 (IL-8)] and nursing satisfaction were compared between the two groups. Results After intervention, the scores of each dimension of pink esthetic index in the observation group were higher than those in the control group (P<0.05). After intervention, the scores of each dimension of white esthetic index in the observation group were higher than those in the control group (P <0.05). The PD, BI and PLI in the observation group were lower than those in the control group (P <0.05). After intervention, the thickness of enamel in the observation group was higher than that in the control group, and the roughness was lower than that in the control group (P <0.05). The total nursing satisfaction rate in the observation group was 97.78%, which was higher than 84.44% in the control group (P<0.05). Conclusion The progressive nursing based on multi-dimensional coordination can improve the aesthetic effect of orthodontics patients,improve the gingival health indexes, dental texture, gingival crevicular fluid inflammatory factors, and achieve higher patient satisfaction.