Objective To compare the changes in lateral profile of adult patients with Angle class Ⅱ division 1 malocclusion before and after orthodontic extraction treatment, and to explore the correlation between the changes in hard tissues and soft tissues before and after treatment. Methods A total of 24 patients with Angle class Ⅱ division 1 who were treated with orthodontic extraction of upper and lower premolars from July 2018 to July 2021 were selected as the research subjects. The changes in hard tissue parameters (skeletal parameters, Y-axis angle, dental parameters) and soft tissue parameters before and after treatment were compared. The relationship between the soft tissue parameters and the hard tissue parameters before and after treatment was evaluated by Pearson correlation analysis. Results There were significant differences in U1-SN, IMPA, U1-NA, U1-SL, L1-SL, U1-L1, Cm-Sn-UL, UL-EP, LL-EP, UL-SL, LL-SL, G-Sn-Pog', Z-Angle, and Si-LLPog' before and after treatment (P <0.05), while there were no significant differences in the other indicators (P >0.05). Pearson correlation analysis showed that the change value of UL-SL was positively correlated with the change values of U1-SN and U1-SL (r =0.583, 0.633, P<0.05), and the change value of LLSL was positively correlated with the change values of U1-SL and L1-SL (r =0.588, 0.412, P<0.05). However, the change value of Cm-Sn- UL had a weak negative correlation with the change values of U1-SN and U1-SL (r =-0.375, -0.352, P=0.040, 0.045). The change values of Cm-Sn-UL, UL-SL and LL-SL were not correlated with the change values of SNA and SNB (P >0.05). Conclusion After orthodontic extraction camouflage treatment in patients with Angle class Ⅱ division 1 malocclusion, there are obvious changes in the teeth and facial soft tissues. The changes in the lip morphology and protrusion of the soft tissues are closely related to the changes in the position of the incisors.