Abstract:Objective To explore the application of digital design and 3D printing technology in minimally invasive restoration with inlay veneers and its influence on aesthetics. Methods A total of 70 patients who underwent minimally invasive restoration with inlay veneers in our hospital from March 2022 to July 2024 were selected as the research subjects. According to the random number table method, they were divided into the control group and the observation group, with 35 patients in each group. The control group was treated with the traditional restoration method, and the observation group was treated with digital design and 3D printing technology. The restoration effect, smoothness, color matching degree, aesthetics and adjacent relationship were compared between the two groups. Results The suitability and marginal adaptation of the observation group were better than those of the control group, and the differences were statistically significant (P <0.05). The smoothness of the restoration in the two groups was better than that before restoration, and that in the observation group was better than that in the control group, and the difference was statistically significant (P <0.05). The color matching degree of the restoration in the observation group (94.29%) was higher than that in the control group (77.14%) , and the difference was statistically significant (P <0.05). After restoration, the aesthetic score in the two groups was higher than that before restoration, and that in the observation group was higher than that in the control group, and the difference was statistically significant (P <0.05). The adjacent relationship of the observation group was better than that of the control group, and the difference was statistically significant (P <0.05). Conclusion Digital design and 3D printing technology have a good application effect in minimally invasive restoration with inlay veneers, which can improve the suitability, marginal adaptation and color matching degree of restoration, enhance aesthetics, and improve the adjacent relationship. It is worthy of clinical application.