Objective To study the effect of orthodontics treatment on dental function and appearance improvement in patients with anterior teeth displacement caused by periodontal disease. Methods A total of 108 patients with anterior teeth displacement caused by periodontal disease admitted to Jinfeng District Jianjun Dental Clinic from March 2022 to March 2024 were selected as the research subjects. According to the random number table method, they were divided into the control group and the observation group, with 54 patients in each group. The control group received conventional treatment, and the observation group received orthodontics treatment. The dental function and appearance improvement, periodontal indicators, quality of life, serum inflammatory factor levels and adverse reactions were compared between the two groups. Results The scores of masticatory function, swallowing function, oral expression and teeth alignment in the observation group were higher than those in the control group (P <0.05). The periodontal pocket depth, anterior teeth coverage, alveolar bone height and probing bleeding rate in the observation group were better than those in the control group (P <0.05). The scores of all dimensions of quality of life in the observation group were higher than those in the control group (P <0.05). The levels of TNF-α and IL-6 in the observation group were lower than those in the control group, the level of IL-2 was higher than that in the control group (P <0.05). The incidence of adverse reactions in the observation group (5.56%) was lower than that in the control group (22.22%) (P <0.05). Conclusion Orthodontics treatment for patients with anterior teeth displacement caused by periodontal disease can effectively improve their dental function and appearance,optimize periodontal indicators and serum inflammatory factor levels, enhance the quality of life, and has a low incidence of adverse reactions.