Objective To analyze the effect of multifunctional laser photoelectric platform combined with acupuncture on skin barrier function in patients with facial dermatitis. Methods A total of 88 patients with facial dermatitis admitted to the Department of Medical Cosmetology, the Third People's Hospital of Hubei Province from September 2022 to September 2024 were selected as the research subjects. According to the random number table method, they were divided into the control group and the observation group, with 44 patients in each group. The control group was treated with multifunctional laser photoelectric platform, and the observation group added acupuncture treatment on the basis of the control group. The clinical symptom improvement and skin barrier function were compared between the two groups. Results After treatment, the symptom scores of itching, tightness, burning, stinging, erythema, papules and pustules in the observation group were lower than those in the control group (P <0.05). After treatment, the skin thickness, skin density and stratum corneum water content in the observation group were higher than those in the control group, and the transepidermal water loss in the observation group was (10.22±1.02)g/(h?m2), which was less than (14.22±2.02)g/(h?m2) in the control group (P <0.05). Conclusion The combination of multifunctional laser photoelectric platform and acupuncture for patients with facial dermatitis can effectively improve skin symptoms and strengthen skin barrier function, which is worthy of clinical application.