Objective To investigate the effect and safety of vertical scar method combined with prosthesis implantation in the correction of breast ptosis. Methods A total of 60 patients with breast ptosis who underwent breast ptosis correction in our hospital from December 2021 to December 2024 were selected as the research subjects. According to different surgical methods, they were divided into the control group and the study group, with 30 patients in each group. The control group was given traditional inverted T correction, and the study group was given vertical scar method combined with prosthesis implantation. The breast measurement indicators, satisfaction and complications were compared between the two groups. Results After surgery, the NN, SSN-N, AD, N-IMF and MBW in the study group were lower than those in the control group, and the TN was higher than that in the control group (P<0.05). The satisfaction scores of the study group after surgery were higher than those of the control group (P <0.05). The incidence of complications in the study group (3.33%) was lower than that in the control group (20.00%) (P <0.05). Conclusion The vertical scar method combined with prosthesis implantation for breast ptosis has a definite clinical effect, which can effectively improve the convexity and shape of the breast, improve patient satisfaction, and has high safety.