Objective To investigate the effect of kite flap repair for round defect of lateral eyebrow on flap survival rate and aesthetic effect. Methods A total of 80 patients with round defect of lateral eyebrow admitted to our hospital from January 2022 to December 2024 were selected as the research subjects. According to the random number table method, they were divided into the control group and the observation group, with 40 patients in each group. The control group was treated with traditional direct suture or local flap repair, and the observation group was treated with kite flap repair. The flap survival rate, aesthetic effect, treatment satisfaction and complications were compared between the two groups. Results The flap survival rate of the observation group was 95.00%, which was higher than 80.00% of the control group (P <0.05). The scores of color, texture, flatness and contour matching degree in the observation group were higher than those in the control group (P <0.05). The treatment satisfaction rate of the observation group was 92.50%, which was higher than 77.50% of the control group (P <0.05). The incidence of complications in the observation group was 7.50%, which was lower than 22.50% in the control group (P <0.05). Conclusion Kite flap repair for round defect of lateral eyebrow can effectively improve flap survival rate, enhance aesthetic effect, improve patient satisfaction, and reduce the incidence of complications.