强脉冲光联合调Q激光对面部雀斑患者雀斑严重程度的影响
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南京江宁苏王美容医院皮肤科

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    摘要:

    目的:本研究旨在探讨采用强脉冲光与调Q激光联合治疗面部雀斑患者的临床疗效及其对皮肤屏障功能的影响。方法:随机选取2023年9月至2024年9月期间在本院接受治疗的面部雀斑患者共60例,进行临床疗效及皮肤屏障功能评估。分组运用随机数字表法,组别类型为观察组和对照组,每组各有患者30例。对照组患者给予单独调Q激光进行治疗,观察组采取强脉冲光联合调Q激光方案治疗,对比分析两种不同治疗方案的治疗效果。结果:研究数据表明,观察组的(采用强脉冲光联合调Q激光治疗)在皮肤屏障功能的恢复以及雀斑程度的改善方面均显著优于对照组。具体而言,观察组的皮肤屏障功能恢复指标与雀斑改善程度均显示出统计学上的显著性差异(P<0.05)。同时,观察组发生治疗相关不良反应的比率也显著低于对照组(P<0.05)。此外,观察组的治疗总有效率显著高于对照组(P<0.05)。在对面部美观度的主观评价方面,观察组的评分也显著高于对照组(P<0.05)。结论:采用强脉冲光与调Q激光联合治疗方案在改善面部雀斑患者的皮肤屏障功能、减轻雀斑程度、降低不良反应发生率以及提升面部美观度方面均展现出显著的优越性。

    Abstract:

    Objective To explore the effect of intense pulsed light combined with Q-switched laser on the severity of freckles in patients with facial freckles. Methods From September 2023 to September 2024, 60 patients with facial freckles who were treated in the dermatology department of Suwang Beauty Hospital in Jiangning, Nanjing were randomly divided into control group and observation group, with 30 patients in each group. The control group was treated with Q-switched laser, while the observation group was treated with intense pulsed light combined with Q-switched laser. The severity of freckles, facial beauty, skin barrier function, clinical efficacy and incidence of adverse reactions were compared between the two groups. Results The PSI score of the observation group was lower than that of the control group after treatment (P < 0.05). After treatment, the facial beauty score of the observation group was higher than that of the control group (P < 0.05). After treatment, the sebum content and skin water content in the observation group were higher than those in the control group, and the skin water loss was lower than that in the control group (P < 0.05). The total effective rate in the observation group (96.67%) was higher than that in the control group (80.00%) (P < 0.05). The incidence of adverse reactions in the observation group (3.33%) was lower than that in the control group (20.00%) (P < 0.05). Conclusion Intense pulsed light combined with Q-switched laser can improve skin barrier function in patients with facial freckles, reduce the severity of freckles, but also reduce the incidence of adverse reactions, and effectively improve the facial aesthetics and overall satisfaction of patients.

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  • 收稿日期:2025-11-25
  • 最后修改日期:2025-12-22
  • 录用日期:2025-12-22
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