Objective To explore the effect of orbital septum fat fascial flap repair on anatomical morphological indicators and natural morphological indicators in patients with excessively wide double eyelid after double eyelid surgery. Methods A total of 60 patients with excessively wide double eyelid after double eyelid surgery admitted to Shanghai Beau Care Medical Clinic from January to December 2024 were selected as the research subjects, and they were divided into the control group and the observation group by the random number table method, with 30 patients in each group. The control group was treated with conventional traditional repair, and the observation group was treated with orbital septum fat fascial flap repair. The clinical efficacy, anatomical morphological indicators, natural morphological indicators and complication rate were compared between the two groups. Results The total effective rate of treatment in the observation group (93.33%) was higher than that in the control group (73.33%) (P <0.05). The double eyelid width, angle difference of medial canthal segment, and central segment angle in the observation group after operation were better than those in the control group (P <0.05). The eyebrow-eyelid distance and palpebral fissure height in the observation group after operation were better than those in the control group (P <0.05). The incidence of complications in the observation group (6.67%) was lower than that in the control group (30.00%) (P <0.05). Conclusion Orbital septum fat fascial flap repair has an ideal clinical effect, which can effectively improve patients' anatomical morphological indicators and natural morphological indicators, with low incidence of complications. It is worthy of clinical application.