Objective To analyze the effect of different wavelength bands of intense pulsed light (IPL) on the improvement of hair density in different parts of hair removal patients. Methods A total of 132 hair removal patients admitted to our hospital from January to October 2024 were selected as the research subjects, and they were divided into the control group and the observation group by the random number table method, with 66 patients in each group. The control group was treated with intense pulsed light of 510-1200 nm wavelength band, and the observation group was treated with intense pulsed light of 600-1200 nm wavelength band. The hair removal effect of different parts, hair density reduction rate, satisfaction and adverse reactions were compared between the two groups. Results There was no significant difference in the total effective rate of hair removal in different parts between the two groups (P >0.05). The hair density reduction rates of lips, lower legs and arms in the observation group were better than those in the control group (P <0.05). There was no significant difference in the hair density reduction rate of armpits between the two groups (P >0.05). The satisfaction rate of the observation group (98.48%) was higher than that of the control group (89.39%) (P<0.05). The incidence of adverse reactions in the observation group (3.03%) was lower than that in the control group (12.12%) (P<0.05). Conclusion Both groups have ideal hair removal effects, but compared with intense pulsed light of 510-1200 nm wavelength band, 600-1200 nm wavelength band has better hair removal effect on lips, lower legs and arms, and can improve patient satisfaction, with lower incidence of adverse reactions, which is worthy of clinical application.