Objective To explore the effect of minimally invasive ultra-thin veneer technology on dental aesthetic effect in patients with anterior diastema restoration. Methods A total of 58 patients with anterior diastema admitted to the Third People's Hospital of Bijie from February 2023 to December 2024 were selected, and they were divided into the control group and the observation group by the random number table method, with 29 patients in each group. The control group was treated with resin restoration, and the observation group was treated with minimally invasive ultra-thin veneer technology. The dental aesthetic effect, periodontal status, masticatory function and quality of life were compared between the two groups. Results The scores of dentition integrity, color matching, natural tooth surface margin and restoration integrity in the observation group were higher than those in the control group (P <0.05). The GI, PD, BI and PLI in the observation group were lower than those in the control group (P <0.05). The occlusal force and masticatory efficiency in the observation group were higher than those in the control group (P <0.05). The scores of each dimension of quality of life in the observation group were higher than those in the control group (P <0.05). Conclusion The application of minimally invasive ultra-thin veneer technology can effectively improve the dental aesthetic effect of patients with anterior diastema restoration, accelerate the recovery of masticatory function, help to improve periodontal status, and enhance patients' quality of life.