Abstract:Objective: This study investigates the clinical efficacy of integrating four-handed dentistry with psychological guidance in pediatric dental outpatient care, focusing on its impact on children's emotional well-being, compliance during procedures, anxiety levels, and parental satisfaction.Methods: A cohort of 280 pediatric patients treated at Wuxi Children's Hospital's dental clinic between May 2022 and September 2025 was randomly assigned to either a control group (standard care) or an intervention group (four-handed technique with psychological support), each comprising 140 participants. Pre- and post-intervention assessments included psychological metrics (HAD-A for anxiety, HAD-D for depression), behavioral compliance indicators (episodes of crying, treatment refusal, physical resistance, verbal non-cooperation, and distractibility), procedural anxiety severity, and caregiver satisfaction rates.Results: Post-intervention data revealed significantly lower HAD-A and HAD-D scores in the intervention group versus controls (P<0.05). Behavioral metrics—crying, treatment refusal, aggression toward staff, communication avoidance, and inattention—were all markedly reduced in the intervention cohort (P<0.05). The intervention group demonstrated a 32.14% incidence of procedural fear, substantially below the control group's 78.57% (P<0.05). Caregiver satisfaction reached 96.43% with the combined approach, outperforming the 75.00% satisfaction rate under conventional care (P<0.05).Conclusion: The synergistic application of four-handed dentistry and psychological intervention yields measurable benefits in pediatric dental settings. It enhances emotional stability, optimizes procedural cooperation (reflected in improved behavioral scores), mitigates treatment-related anxiety, and elevates family satisfaction, underscoring its viability for widespread clinical adoption.