Objective:To explore the effect of implementing problem-oriented nursing after limb trauma flap repair surgery. Methods: From May 2023 to May 2025, 60 patients with limb trauma admitted to the Third People"s Hospital of Guizhou Province were selected as the research subjects. All of them received flap repair surgery. During the study, the patients were randomly divided into the control group (receiving routine nursing intervention) and the observation group (receiving problem-oriented nursing intervention) at a ratio of 1:1, with 30 cases in each group. The survival rate of the flaps, the degree of functional recovery of the affected limb [evaluated using the Fugl-Meyer Limb Function Assessment Scale (FMA)], the psychological state [assessed using the Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS)], and the nursing satisfaction were compared between the two groups. Results: The survival rates of the two groups of flaps were 100.00% versus 83.33%, with the observation group having a higher rate (P<0.05). Four weeks after the intervention, the upper limb function score and lower limb motor function score of the observation group were both higher than those of the control group (P<0.05). The SAS score and SDS score of the observation group were lower after the intervention (P<0.05). The nursing satisfaction rate of the observation group was 100.00%, which was higher than 83.33% of the control group (P<0.05). Conclusion: The application of problem-oriented nursing in the postoperative care of limb trauma flap repair can improve the survival rate of the flaps and nursing satisfaction, promote the improvement of the psychological state and the recovery of the function of the affected limb.