Maxillary protrusion is a common type of malocclusion in clinical orthodontics, which not only impairs masticatory function, but also exerts a significant impact on facial appearance. In fact, facial improvement is often the primary motivation for patients to seek orthodontics treatment. Micro-implant anchorage has demonstrated deffnite efffcacy in correcting maxillary protrusion and improving patients' facial profile, and has become a commonly used clinical orthodontics method. This paper systematically summarizes the key points of clinical application of micro-implant anchorage screw in orthodontics treatment, with a focus on exploring the critical inffuencing factors such as implantation site selection, diameter size, implantation method and postoperative loading timing. It is intended to provide a reference basis for the standardized clinical application of this technology, thereby beneffting more patients with maxillary protrusion.